Andrzej J Jakubowiak Selected Research

Protein Kinases (Protein Kinase)

1/2020

Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.

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Andrzej J Jakubowiak Research Topics

Disease

45	Multiple Myeloma 10/2022 - 10/2008
6	Neoplasms (Cancer) 01/2020 - 12/2007
4	Peripheral Nervous System Diseases (PNS Diseases) 08/2014 - 07/2010
3	Disease Progression 01/2020 - 04/2011
3	Thrombocytopenia (Thrombopenia) 01/2016 - 10/2008
2	Residual Neoplasm 01/2022 - 01/2021
2	Fatigue 08/2014 - 08/2010
2	Neutropenia 08/2014 - 10/2008
1	Plasma Cell Neoplasms 04/2022
1	Febrile Neutropenia 01/2016
1	Lymphoma (Lymphomas) 01/2016
1	Muscle Cramp (Cramp) 01/2016
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2015
1	Acute-Phase Reaction 07/2015
1	Exanthema (Rash) 08/2014
1	Nausea 08/2014
1	Chest Pain (Chest Pains) 06/2012
1	Gastroenteritis 06/2012
1	Septic Shock (Toxic Shock Syndrome) 03/2011
1	Infections 03/2011
1	Human Influenza (Influenza) 03/2011
1	Cardiac Arrhythmias (Arrythmia) 03/2011
1	Pulmonary Embolism 10/2008
1	Venous Thrombosis (Deep-Vein Thrombosis) 10/2008
1	Hemorrhage 10/2008

Drug/Important Bio-Agent (IBA)

19	carfilzomibIBA 10/2022 - 06/2012
18	Dexamethasone (Maxidex)FDA LinkGeneric 10/2022 - 10/2008
15	Lenalidomide (CC 5013)FDA Link 10/2022 - 08/2010
15	Bortezomib (Velcade)FDA Link 12/2017 - 10/2008
9	Proteasome InhibitorsIBA 01/2019 - 12/2007
4	Thalidomide (Thalomid)FDA Link 08/2014 - 07/2009
3	Pharmaceutical PreparationsIBA 01/2022 - 08/2014
3	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019 - 12/2007
2	selinexorIBA 01/2019 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 11/2016 - 12/2007
2	marizomibIBA 01/2016 - 08/2014
2	elotuzumabIBA 12/2015 - 06/2012
2	Immunomodulating AgentsIBA 07/2015 - 02/2013
2	Monoclonal AntibodiesIBA 06/2012 - 09/2011
2	liposomal doxorubicin (Doxil)FDA Link 07/2011 - 10/2009
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	daratumumabIBA 01/2022
1	Drug CombinationsIBA 01/2022
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2020
1	Immunoconjugates (Immunoconjugate)IBA 01/2020
1	EpitopesIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2020
1	PDZ-binding kinaseIBA 01/2020
1	OTS964IBA 01/2020
1	Protein Kinases (Protein Kinase)IBA 01/2020
1	ONX 0912IBA 01/2019
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019
1	PanobinostatIBA 01/2019
1	KinesinsIBA 11/2016
1	filanesibIBA 11/2016
1	pevonedistatIBA 01/2016
1	Transaminases (Aminotransferases)IBA 01/2016
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2016
1	EnzymesIBA 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 07/2015
1	ixazomibIBA 08/2014
1	perifosineIBA 08/2012
1	Proto-Oncogene Proteins B-rafIBA 03/2011
1	SteroidsIBA 03/2011
1	MTOR InhibitorsIBA 03/2011
1	temsirolimus FDA Link 03/2011
1	Amyloid (Amyloid Fibrils)IBA 03/2011
1	1-dodecylpyridoxal (PLD)IBA 10/2009
1	Melphalan (Alkeran)FDA LinkGeneric 07/2009
1	Prednisone (Sone)FDA LinkGeneric 07/2009
1	Erythropoietin FDA Link 10/2008
1	Messenger RNA (mRNA)IBA 12/2007

Therapy/Procedure

15	Therapeutics 04/2022 - 07/2009
2	Precision Medicine 01/2022 - 07/2015
2	Stem Cell Transplantation 01/2021 - 11/2020
1	Drug Therapy (Chemotherapy) 01/2020
1	Aftercare (After-Treatment) 11/2016
1	Autologous Transplantation 07/2009